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Sustained suppression of Bcr-Abl-driven lymphoid leukemia by microRNA mimics

Many cancers and leukemias are associated with strong dominant oncogenic mutations that activate tyrosine kinases and other classes of molecules, including transcription factors and antiapoptotic mechanisms. Some of these events can be targeted with small molecules or antibody-based therapeutics, bu...

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Detalhes bibliográficos
Main Authors: McLaughlin, Jami, Cheng, Donghui, Singer, Oded, Lukacs, Rita U., Radu, Caius G., Verma, Inder M., Witte, Owen N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2154460/
https://ncbi.nlm.nih.gov/pubmed/18079287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710532105
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