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Sustained suppression of Bcr-Abl-driven lymphoid leukemia by microRNA mimics

Many cancers and leukemias are associated with strong dominant oncogenic mutations that activate tyrosine kinases and other classes of molecules, including transcription factors and antiapoptotic mechanisms. Some of these events can be targeted with small molecules or antibody-based therapeutics, bu...

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Autors principals: McLaughlin, Jami, Cheng, Donghui, Singer, Oded, Lukacs, Rita U., Radu, Caius G., Verma, Inder M., Witte, Owen N.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2154460/
https://ncbi.nlm.nih.gov/pubmed/18079287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710532105
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