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Human neutrophils uniquely release TIMP-free MMP-9 to provide a potent catalytic stimulator of angiogenesis

Several lines of evidence have implicated matrix metalloproteinase 9 (MMP-9) as a protease inducing an angiogenic switch critical for tumor progression. Among MMP-9-expressing cell types, including cancer cells and tumor-associated leukocytes, inflammatory neutrophils appear to provide an important...

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Autors principals: Ardi, Veronica C., Kupriyanova, Tatyana A., Deryugina, Elena I., Quigley, James P.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2154419/
https://ncbi.nlm.nih.gov/pubmed/18077379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706438104
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