Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion

The invasion of human malignant melanoma cells into the extracellular matrix (ECM) involves the accumulation of proteases at sites of ECM degradation where activation of matrix metalloproteases (MMP) occurs. Here, we show that when membrane type 1 MMP (MT-MMP) was overexpressed in RPMI7951 human mel...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Nakahara, Hirokazu, Howard, Linda, Thompson, Erik W., Sato, Hiroshi, Seiki, Motoharu, Yeh, Yunyun, Chen, Wen-Tien
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences of the USA 1997
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC21537/
https://ncbi.nlm.nih.gov/pubmed/9223295
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