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Tumor induction by a transformation-defective polyoma virus mutant blocked in signaling through Shc
Transformation of cells in culture by polyoma virus requires integration of signals downstream of middle T–Shc and middle T-phosphatidylinositol 3-kinase interactions, but the same is not true for induction of tumors in the mouse. Thus, a middle T mutant defective in transformation and blocked in bi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The National Academy of Sciences of the USA
1997
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC21536/ https://ncbi.nlm.nih.gov/pubmed/9223294 |
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