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RecBCD enzyme switches lead motor subunits in response to χ-recognition

RecBCD is a DNA helicase comprising two motor subunits, RecB and RecD. Recognition of the recombination hotspot, χ, causes RecBCD to pause and reduce translocation speed. To understand this control of translocation, we used single-molecule visualization to compare RecBCD to the RecBCD(K177Q) mutant...

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Bibliografiske detaljer
Main Authors: Spies, Maria, Amitani, Ichiro, Baskin, Ronald J., Kowalczykowski, Stephen C.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151923/
https://ncbi.nlm.nih.gov/pubmed/18022364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.09.023
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