Inducibility of the endogenous antibiotic peptide β-defensin 2 is impaired in patients with severe sepsis

INTRODUCTION: The potent endogenous antimicrobial peptide human β-defensin 2 (hBD2) is a crucial mediator of innate immunity. In addition to direct antimicrobial properties, different effects on immune cells have been described. In contrast to the well-documented epithelial β-defensin actions in loc...

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Detalhes bibliográficos
Main Authors: Book, Malte, Chen, QiXing, Lehmann, Lutz E, Klaschik, Sven, Weber, Stefan, Schewe, Jens-Christian, Luepertz, Markus, Hoeft, Andreas, Stuber, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151902/
https://ncbi.nlm.nih.gov/pubmed/17302973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc5694
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