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Mode Switching Is the Major Mechanism of Ligand Regulation of InsP(3) Receptor Calcium Release Channels
The inositol 1,4,5-trisphosphate (InsP(3)) receptor (InsP(3)R) plays a critical role in generation of complex Ca(2+) signals in many cell types. In patch clamp recordings of isolated nuclei from insect Sf9 cells, InsP(3)R channels were consistently detected with regulation by cytoplasmic InsP(3) and...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2151663/ https://ncbi.nlm.nih.gov/pubmed/17998395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200709859 |
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