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β-Scorpion Toxin Modifies Gating Transitions in All Four Voltage Sensors of the Sodium Channel

Several naturally occurring polypeptide neurotoxins target specific sites on the voltage-gated sodium channels. Of these, the gating modifier toxins alter the behavior of the sodium channels by stabilizing transient intermediate states in the channel gating pathway. Here we have used an integrated a...

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Autori principali: Campos, Fabiana V., Chanda, Baron, Beirão, Paulo S.L., Bezanilla, Francisco
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151646/
https://ncbi.nlm.nih.gov/pubmed/17698594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200609719
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