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A Role for the S0 Transmembrane Segment in Voltage-dependent Gating of BK Channels

BK (Maxi-K) channel activity is allosterically regulated by a Ca(2+) sensor, formed primarily by the channel's large cytoplasmic carboxyl tail segment, and a voltage sensor, formed by its transmembrane helices. As with other voltage-gated K channels, voltage sensing in the BK channel is accompl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Koval, Olga M., Fan, Yun, Rothberg, Brad S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151615/
https://ncbi.nlm.nih.gov/pubmed/17296928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200609662
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