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Muscle Chloride Channel Dysfunction in Two Mouse Models of Myotonic Dystrophy
Muscle degeneration and myotonia are clinical hallmarks of myotonic dystrophy type 1 (DM1), a multisystemic disorder caused by a CTG repeat expansion in the 3′ untranslated region of the myotonic dystrophy protein kinase (DMPK) gene. Transgenic mice engineered to express mRNA with expanded (CUG)(250...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2151606/ https://ncbi.nlm.nih.gov/pubmed/17158949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200609635 |
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