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Single Cl(−) Channels Activated by Ca(2+) in Drosophila S2 Cells Are Mediated By Bestrophins

Mutations in human bestrophin-1 (VMD2) are genetically linked to several forms of retinal degeneration but the underlying mechanisms are unknown. Bestrophin-1 (hBest1) has been proposed to be a Cl(−) channel involved in ion and fluid transport by the retinal pigment epithelium (RPE). To date, howeve...

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Autori principali: Chien, Li-Ting, Zhang, Zhi-Ren, Hartzell, H. Criss
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151570/
https://ncbi.nlm.nih.gov/pubmed/16940553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200609581
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