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EGFR Kinase Regulates Volume-sensitive Chloride Current Elicited by Integrin Stretch via PI-3K and NADPH Oxidase in Ventricular Myocytes
Stretch of β1 integrins activates an outwardly rectifying, tamoxifen-sensitive Cl(−) current (Cl(−) SAC) via AT1 receptors, NADPH oxidase, and reactive oxygen species, and Cl(−) SAC resembles the volume-sensitive Cl(−) current (I(Cl,swell)). Epidermal growth factor receptor (EGFR) kinase undergoes t...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2151502/ https://ncbi.nlm.nih.gov/pubmed/16505146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200509366 |
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