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Crystal Structure of Cefditoren Complexed with Streptococcus pneumoniae Penicillin-Binding Protein 2X: Structural Basis for Its High Antimicrobial Activity

Cefditoren is the active form of cefditoren pivoxil, an oral cephalosporin antibiotic used for the treatment of respiratory tract infections and otitis media caused by bacteria such as Streptococcus pneumoniae, Haemophilus influenzae, Streptococcus pyogenes, Klebsiella pneumoniae, and methicillin-su...

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Main Authors: Yamada, Mototsugu, Watanabe, Takashi, Miyara, Takako, Baba, Nobuyoshi, Saito, Jun, Takeuchi, Yasuo, Ohsawa, Fukuichi
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151468/
https://ncbi.nlm.nih.gov/pubmed/17724158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00743-07
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