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Adenosine Kinase of Trypanosoma brucei and Its Role in Susceptibility to Adenosine Antimetabolites

Trypanosoma brucei cannot synthesize purines de novo and relies on purine salvage from its hosts to build nucleic acids. With adenosine being a preferred purine source of bloodstream-form trypanosomes, adenosine kinase (AK; EC 2.7.1.20) is likely to be a key player in purine salvage. Adenosine kinas...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lüscher, Alexandra, Önal, Pinar, Schweingruber, Anne-Marie, Mäser, Pascal
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151413/
https://ncbi.nlm.nih.gov/pubmed/17698621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00458-07
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