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Stimulation of the apoptotic response as a basis for the therapeutic synergism of lonidamine and cisplatin in combination in human tumour xenografts.

The pharmacological interest in lonidamine is related to its ability to enhance the cytotoxic effects of several DNA-damaging anti-tumour agents. This study was undertaken to better understand the in vivo interaction between lonidamine and cisplatin in the treatment of human tumour xenografts, inclu...

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Autors principals: De Cesare, M., Pratesi, G., Giusti, A., Polizzi, D., Zunino, F.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151278/
https://ncbi.nlm.nih.gov/pubmed/9472640
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