Evaluation of Prime/Boost Regimens Using Recombinant Poxvirus/Tyrosinase Vaccines for the Treatment of Patients with Metastatic Melanoma

PURPOSE: Two clinical trials were conducted to evaluate the clinical efficacy and immunologic impact of vaccination against the tyrosinase protein plus systemic interleukin 2 (IL-2) administration in patients with advanced metastatic melanoma. EXPERIMENTAL DESIGN: Full-length tyrosinase was employed...

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Detalhes bibliográficos
Main Authors: Lindsey, Kimberly R., Gritz, Linda, Sherry, Richard, Abati, Andrea, Fetsch, Patricia A., Goldfeder, Lisa C., Gonzales, Monica I., Zinnack, Kimberly A., Rogers-Freezer, Linda, Haworth, Leah, Mavroukakis, Sharon A., White, Donald E., Steinberg, Seth M., Restifo, Nicholas P., Panicali, Dennis L., Rosenberg, Steven A., Topalian, Suzanne L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151202/
https://ncbi.nlm.nih.gov/pubmed/16638862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-05-2061
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