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Sphingosine Kinase Expression Increases Intracellular Sphingosine-1-Phosphate and Promotes Cell Growth and Survival

Sphingosine-1-phosphate (SPP) is a bioactive lipid that has recently been identified as the ligand for the EDG family of G protein–coupled cell surface receptors. However, the mitogenic and survival effects of exogenous SPP may not correlate with binding to cell-surface receptors (Van Brocklyn, J.R....

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Dettagli Bibliografici
Autori principali: Olivera, Ana, Kohama, Takafumi, Edsall, Lisa, Nava, Victor, Cuvillier, Olivier, Poulton, Samantha, Spiegel, Sarah
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151183/
https://ncbi.nlm.nih.gov/pubmed/10545499
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