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APC/C-Cdh1-mediated degradation of the Polo kinase Cdc5 promotes the return of Cdc14 into the nucleolus

In the budding yeast Saccharomyces cerevisiae, the protein phosphatase Cdc14 triggers exit from mitosis by promoting the inactivation of cyclin-dependent kinases (CDKs). Cdc14’s activity is controlled by Cfi1/Net1, which holds and inhibits the phosphatase in the nucleolus from G1 until metaphase. Du...

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Hlavní autoři: Visintin, Clara, Tomson, Brett N., Rahal, Rami, Paulson, Jennifer, Cohen, Michael, Taunton, Jack, Amon, Angelika, Visintin, Rosella
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151016/
https://ncbi.nlm.nih.gov/pubmed/18172166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1601308
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