Functionally distinct regulatory RNAs generated by bidirectional transcription and processing of microRNA loci

Many microRNA (miRNA) loci exhibit compelling hairpin structures on both sense and antisense strands; however, the possibility that a miRNA gene might produce functional species from its antisense strand has not been examined. We report here that antisense transcription of the Hox miRNA locus mir-ia...

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Autori principali: Tyler, David M., Okamura, Katsutomo, Chung, Wei-Jen, Hagen, Joshua W., Berezikov, Eugene, Hannon, Gregory J., Lai, Eric C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2008
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151012/
https://ncbi.nlm.nih.gov/pubmed/18172163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1615208
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