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The dermis contains langerin(+) dendritic cells that develop and function independently of epidermal Langerhans cells

Langerhans cells (LCs) constitute a subset of dendritic cells (DCs) that express the lectin langerin and that reside in their immature state in epidermis. Paradoxically, in mice permitting diphtheria toxin (DT)–mediated ablation of LCs, epidermal LCs reappeared with kinetics that lagged behind that...

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Dettagli Bibliografici
Autori principali: Poulin, Lionel Franz, Henri, Sandrine, de Bovis, Béatrice, Devilard, Elisabeth, Kissenpfennig, Adrien, Malissen, Bernard
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2150992/
https://ncbi.nlm.nih.gov/pubmed/18086861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071724
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