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The dermis contains langerin(+) dendritic cells that develop and function independently of epidermal Langerhans cells

Langerhans cells (LCs) constitute a subset of dendritic cells (DCs) that express the lectin langerin and that reside in their immature state in epidermis. Paradoxically, in mice permitting diphtheria toxin (DT)–mediated ablation of LCs, epidermal LCs reappeared with kinetics that lagged behind that...

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Detalhes bibliográficos
Main Authors: Poulin, Lionel Franz, Henri, Sandrine, de Bovis, Béatrice, Devilard, Elisabeth, Kissenpfennig, Adrien, Malissen, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2150992/
https://ncbi.nlm.nih.gov/pubmed/18086861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071724
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