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Expression, refolding and crystallizations of the Grb2-like (GADS) C-terminal SH3 domain complexed with a SLP-76 motif peptide

The Grb2-like adaptor protein GADS is composed of an N-terminal SH3 domain, an SH2 domain, a proline-rich region and a C-terminal SH3 domain. GADS interacts through its C-terminal SH3 domain with the adaptor protein SLP-76, thus recruiting this protein and other associated molecules to the linker fo...

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Autors principals: Faravelli, Alessandro, Dimasi, Nazzareno
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2150940/
https://ncbi.nlm.nih.gov/pubmed/16511262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309105041023
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