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Crystallization and preliminary X-ray crystallographic study of the extracellular domain of the 4-1BB ligand, a member of the TNF family

The 4-1BB ligand, a member of the tumour necrosis factor (TNF) family, is an important co-stimulatory molecule that plays a key role in the clonal expansion and survival of CD8+ T cells. Signalling through binding of the 4-1BB ligand and 4-­1BB has been reported to enhance CD8+ T-cell expansion and...

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Autors principals: Byun, Jung-Sue, Kim, Dong-Uk, Ahn, Byungchan, Kwon, Byoung Se, Cho, Hyun-Soo
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2150926/
https://ncbi.nlm.nih.gov/pubmed/16511253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309105039242
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