Direct interaction of insulin-like growth factor-1 receptor with leukemia-associated RhoGEF

Insulin-like growth factor (IGF)-1 plays crucial roles in growth control and rearrangements of the cytoskeleton. IGF-1 binds to the IGF-1 receptor and thereby induces the autophosphorylation of this receptor at its tyrosine residues. The phosphorylation of the IGF-1 receptor is thought to initiate a...

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Autores principales: Taya, Shinichiro, Inagaki, Naoyuki, Sengiku, Hiroaki, Makino, Hiroshi, Iwamatsu, Akihiro, Urakawa, Itaru, Nagao, Kenji, Kataoka, Shiro, Kaibuchi, Kozo
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2001
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2150867/
https://ncbi.nlm.nih.gov/pubmed/11724822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200106139
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