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Cytoplasmic anchorage of L-selectin controls leukocyte capture and rolling by increasing the mechanical stability of the selectin tether

L-selectin is a leukocyte lectin that mediates leukocyte capture and rolling in the vasculature. The cytoplasmic domain of L-selectin has been shown to regulate leukocyte rolling. In this study, the regulatory mechanisms by which this domain controls L-selectin adhesiveness were investigated. We rep...

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Autores principales: Dwir, Oren, Kansas, Geoffrey S., Alon, Ronen
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2150804/
https://ncbi.nlm.nih.gov/pubmed/11581291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200103042
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