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Role of Cholesterol in Formation and Function of a Signaling Complex Involving αvβ3, Integrin-Associated Protein (Cd47), and Heterotrimeric G Proteins

Integrin-associated protein (CD47) is a multiply membrane spanning member of the immunoglobulin superfamily that regulates some adhesion-dependent cell functions through formation of a complex with αvβ3 integrin and trimeric G proteins. Cholesterol is critical for the association of the three protei...

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Detalhes bibliográficos
Main Authors: Green, Jennifer M., Zheleznyak, Alexander, Chung, Jun, Lindberg, Frederik P., Sarfati, Marika, Frazier, William A., Brown, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2150554/
https://ncbi.nlm.nih.gov/pubmed/10444074
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