Interleukin 2 restores CD3-zeta chain expression but fails to generate tumour-specific lytic activity in tumour-infiltrating lymphocytes derived from human colorectal hepatic metastases.

Metastatic colorectal cancer is usually progressive despite infiltration of the tumours by T lymphocytes, suggesting that these tumour-infiltrating lymphocytes (TILs) are functionally deficient. Recently, TILs from other tumours have been shown to express reduced levels of the T-cell receptor signal...

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Detalles Bibliográficos
Main Authors: Yoong, K. F., Adams, D. H.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1998
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2150140/
https://ncbi.nlm.nih.gov/pubmed/9569042
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