Multicellular membranes as an in vitro model for extravascular diffusion in tumours.

Efficient extravascular diffusion is a critical requirement for hypoxic cell radiosensitisers, bioreductive drugs and hypoxic cell markers that must reach cells distant from functional blood vessels in tumours. The diffusion of simple nitroimidazoles with neutral (misonidazole, miso) and basic (pimo...

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Bibliographic Details
Main Authors: Cowan, D. S., Hicks, K. O., Wilson, W. R.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1996
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2149990/
https://ncbi.nlm.nih.gov/pubmed/8763841
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