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Further clinical experiences of a phase I study with the hypoxic cell radiosensitizer misonidazole.

Since April 1976 we have performed clinical investigations with multiple doses of the hypoxic cell radiosensitizer misonidazole in 21 patients. A significant side effect of the drug was the development of peripheral sensory neuropathies in 13 patients (8 mild, 5 severe) and of a transient acute orga...

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Autori principali: Kogelnik, H. D., Meyer, J. H., Jentzsch, K., Szepesi, T., Kärcher, K. H., Maida, E., Mamoli, B., Wessely, P., Zaunbauer, F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1978
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2149409/
https://ncbi.nlm.nih.gov/pubmed/209810
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