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Cytotoxicity of radiosensitizers in multicell spheroids: combination treatment with hyperthermia.

Spheroids of EMT6 tumour cells were grown in spinner culture. As with V79 cell spheroids, the combination of 1.5mM misonidazole and hyperthermia at 42.5 degree C for 1 or 2 h cuased greater cytotoxicity than either heat or drug alone. Radioresistant hypoxic cells at the centre of the spheroids were...

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Bibliografiska uppgifter
Huvudupphovsmän: Sutherland, R., Macfarlane, W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 1978
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2149386/
https://ncbi.nlm.nih.gov/pubmed/277220
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