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Cytotoxicity of radiosensitizers in multicell spheroids: combination treatment with hyperthermia.
Spheroids of EMT6 tumour cells were grown in spinner culture. As with V79 cell spheroids, the combination of 1.5mM misonidazole and hyperthermia at 42.5 degree C for 1 or 2 h cuased greater cytotoxicity than either heat or drug alone. Radioresistant hypoxic cells at the centre of the spheroids were...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
1978
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2149386/ https://ncbi.nlm.nih.gov/pubmed/277220 |
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