The use of recombinant DNA plasmids for the determination of DNA-repair and recombination in cultured mammalian cells.

Using the recombinant plasmid pSV2gpt and DNA transfer techniques, cell mediated DNA ligation and recombination of plasmid DNA have been demonstrated in four human cell lines. Data suggesting the involvement of a possible defect in the cellular equilibrium between ligation and exonuclease digestion...

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Bibliographic Details
Main Authors: Cox, R., Masson, W. K., Debenham, P. G., Webb, M. B.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1984
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2149177/
https://ncbi.nlm.nih.gov/pubmed/6320855
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