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Interpretation of the shape of survival curves in terms of induction and repair/misrepair of DNA double-strand breaks.
Evidence is presented that in yeast cells one DNA double-strand break (dsb) may be considered as one potentially lethal lesion (PLL). Using a temperature conditional radiosensitive diploid yeast mutant (rad 54-3) it is demonstrated that the shoulder of survival curves, for cells plated immediately,...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
1984
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2149141/ https://ncbi.nlm.nih.gov/pubmed/6365140 |
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