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Occludin-deficient Embryonic Stem Cells Can Differentiate into Polarized Epithelial Cells Bearing Tight Junctions

Occludin is the only known integral membrane protein of tight junctions (TJs), and is now believed to be directly involved in the barrier and fence functions of TJs. Occludin-deficient embryonic stem (ES) cells were generated by targeted disruption of both alleles of the occludin gene. When these ce...

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Detalhes bibliográficos
Main Authors: Saitou, Mitinori, Fujimoto, Kazushi, Doi, Yoshinori, Itoh, Masahiko, Fujimoto, Toyoshi, Furuse, Mikio, Takano, Hiroshi, Noda, Tetsuo, Tsukita, Shoichiro
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148457/
https://ncbi.nlm.nih.gov/pubmed/9548718
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