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The preleukemic state of mice reconstituted with Mixl1-transduced marrow cells

Murine granulocytic cells, in becoming leukemic, need to acquire enhanced self-generation and a capacity for autocrine growth stimulation. Mice transplanted with bone marrow cells transduced with the Mixl1 homeobox gene develop a very high frequency of myeloid leukemia derived from the transduced ce...

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Autori principali: Metcalf, Donald, Glaser, Stefan, Mifsud, Sandra, Di Rago, Ladina, Robb, Lorraine
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148414/
https://ncbi.nlm.nih.gov/pubmed/18056627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710339104
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