Allograft rejection mediated by memory T cells is resistant to regulation

Alloreactive memory T cells may be refractory to many of the tolerance-inducing strategies that are effective against naive T cells and thus present a significant barrier to long-term allograft survival. Because CD4(+)CD25(+) regulatory T cells (Tregs) are critical elements of many approaches to suc...

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Main Authors: Yang, Jaeseok, Brook, Matthew O., Carvalho-Gaspar, Manuela, Zhang, Jidong, Ramon, Hilda E., Sayegh, Mohamed H., Wood, Kathryn J., Turka, Laurence A., Jones, Nick D.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2007
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148404/
https://ncbi.nlm.nih.gov/pubmed/18042727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704397104
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