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In vivo multiphoton microscopy of NADH and FAD redox states, fluorescence lifetimes, and cellular morphology in precancerous epithelia

Metabolic imaging of the relative amounts of reduced NADH and FAD and the microenvironment of these metabolic electron carriers can be used to noninvasively monitor changes in metabolism, which is one of the hallmarks of carcinogenesis. This study combines cellular redox ratio, NADH and FAD lifetime...

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Bibliografiske detaljer
Main Authors: Skala, Melissa C., Riching, Kristin M., Gendron-Fitzpatrick, Annette, Eickhoff, Jens, Eliceiri, Kevin W., White, John G., Ramanujam, Nirmala
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148317/
https://ncbi.nlm.nih.gov/pubmed/18042710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708425104
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