In vivo multiphoton microscopy of NADH and FAD redox states, fluorescence lifetimes, and cellular morphology in precancerous epithelia

Metabolic imaging of the relative amounts of reduced NADH and FAD and the microenvironment of these metabolic electron carriers can be used to noninvasively monitor changes in metabolism, which is one of the hallmarks of carcinogenesis. This study combines cellular redox ratio, NADH and FAD lifetime...

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Detalles Bibliográficos
Main Authors: Skala, Melissa C., Riching, Kristin M., Gendron-Fitzpatrick, Annette, Eickhoff, Jens, Eliceiri, Kevin W., White, John G., Ramanujam, Nirmala
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148317/
https://ncbi.nlm.nih.gov/pubmed/18042710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708425104
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