HDAC inhibitor PCI-24781 decreases RAD51 expression and inhibits homologous recombination

Histone deacetylase (HDAC) inhibitors such as the phenyl hydroxamic acid PCI-24781 have emerged recently as a class of therapeutic agents for the treatment of cancer. Recent data showing synergy of HDAC inhibitors with ionizing radiation and other DNA-damaging agents have suggested that HDAC inhibit...

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Detaylı Bibliyografya
Asıl Yazarlar: Adimoolam, Shanthi, Sirisawad, Mint, Chen, Jun, Thiemann, Patti, Ford, James M., Buggy, Joseph J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2007
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148315/
https://ncbi.nlm.nih.gov/pubmed/18042714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707828104
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