Hypoxia stimulates insulin-like growth factor binding protein 1 (IGFBP-1) gene expression in HepG2 cells: A possible model for IGFBP-1 expression in fetal hypoxia

IGFBP-1 is elevated in fetuses with long-term, chronic hypoxia and intrauterine growth restriction. We investigated the hypothesis that hypoxia regulates IGFBP-1 in the human fetus in vivo and IGFBP-1 gene expression and protein in vitro. Umbilical artery IGFBP-1 levels (mean ± SEM) from term babies...

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Библиографические подробности
Главные авторы: Tazuke, Salli I., Mazure, Natalie M., Sugawara, Junichi, Carland, Grace, Faessen, Gerry H., Suen, Lii-Feng, Irwin, Juan C., Powell, David R., Giaccia, Amato J., Giudice, Linda C.
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 1998
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC21483/
https://ncbi.nlm.nih.gov/pubmed/9707622
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