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Mitochondrial origin-binding protein UMSBP mediates DNA replication and segregation in trypanosomes

Kinetoplast DNA (kDNA) is the remarkable mitochondrial genome of trypanosomatids. Its major components are several thousands of topologically linked DNA minicircles, whose replication origins are bound by the universal minicircle sequence-binding protein (UMSBP). The cellular function of UMSBP has b...

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Autori principali: Milman, Neta, Motyka, Shawn A., Englund, Paul T., Robinson, Derrick, Shlomai, Joseph
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148276/
https://ncbi.nlm.nih.gov/pubmed/18048338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706858104
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