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The In Vivo Association of BiP with Newly Synthesized Proteins Is Dependent on the Rate and Stability of Folding and Not Simply on the Presence of Sequences That Can Bind to BiP

Immunoglobulin heavy chain-binding protein (BiP) is a member of the hsp70 family of chaperones and one of the most abundant proteins in the ER lumen. It is known to interact transiently with many nascent proteins as they enter the ER and more stably with protein subunits produced in stoichiometric e...

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Main Authors: Hellman, Rachel, Vanhove, Marc, Lejeune, Annabelle, Stevens, Fred J., Hendershot, Linda M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Rockefeller University Press 1999
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148116/
https://ncbi.nlm.nih.gov/pubmed/9885241
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