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Kinetic Pathway of Pyrophosphorolysis by a Retrotransposon Reverse Transcriptase

DNA and RNA polymerases use a common phosphoryl transfer mechanism for base addition that requires two or three acidic amino acid residues at their active sites. We previously showed, for the reverse transcriptase (RT) encoded by the yeast retrotransposon Ty1, that one of the three conserved active...

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Autors principals: Pandey, Manjula, Patel, Smita S., Gabriel, Abram
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148107/
https://ncbi.nlm.nih.gov/pubmed/18167548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001389
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