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Kinetic Pathway of Pyrophosphorolysis by a Retrotransposon Reverse Transcriptase

DNA and RNA polymerases use a common phosphoryl transfer mechanism for base addition that requires two or three acidic amino acid residues at their active sites. We previously showed, for the reverse transcriptase (RT) encoded by the yeast retrotransposon Ty1, that one of the three conserved active...

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Bibliografiske detaljer
Main Authors: Pandey, Manjula, Patel, Smita S., Gabriel, Abram
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148107/
https://ncbi.nlm.nih.gov/pubmed/18167548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001389
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