Molecular karyotype (amplotype) of metastatic colorectal cancer by unbiased arbitrarily primed PCR DNA fingerprinting

Genomic instability characterizes the aneuploid cancer cell. Losses of genetic material are critical in cancer by exposing recessive mutations in tumor suppressor genes. Gains of genetic material also may lead to overexpression of genes contributing to tumor progression either in the presence or abs...

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Hauptverfasser: Malkhosyan, Sergei, Yasuda, Jun, Soto, Jose Luis, Sekiya, Takao, Yokota, Jun, Perucho, Manuel
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1998
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC21480/
https://ncbi.nlm.nih.gov/pubmed/9707619
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