Molecular karyotype (amplotype) of metastatic colorectal cancer by unbiased arbitrarily primed PCR DNA fingerprinting

Genomic instability characterizes the aneuploid cancer cell. Losses of genetic material are critical in cancer by exposing recessive mutations in tumor suppressor genes. Gains of genetic material also may lead to overexpression of genes contributing to tumor progression either in the presence or abs...

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Bibliografiska uppgifter
Huvudupphovsmän: Malkhosyan, Sergei, Yasuda, Jun, Soto, Jose Luis, Sekiya, Takao, Yokota, Jun, Perucho, Manuel
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 1998
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC21480/
https://ncbi.nlm.nih.gov/pubmed/9707619
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