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Fine-Tuning of Translation Termination Efficiency in Saccharomyces cerevisiae Involves Two Factors in Close Proximity to the Exit Tunnel of the Ribosome

In eukaryotes, release factors 1 and 3 (eRF1 and eRF3) are recruited to promote translation termination when a stop codon on the mRNA enters at the ribosomal A-site. However, their overexpression increases termination efficiency only moderately, suggesting that other factors might be involved in the...

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Autors principals: Hatin, Isabelle, Fabret, Céline, Namy, Olivier, Decatur, Wayne A., Rousset, Jean-Pierre
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2147991/
https://ncbi.nlm.nih.gov/pubmed/17483428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.070771
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