Prognostic Factors Related to Clinical Response in Patients with Metastatic MelanomaTreated by CTL-Associated Antigen-4 Blockade

PURPOSE: CTL-associated antigen 4 (CTLA-4) can inhibit T-cell activation and helps maintain peripheral self-tolerance. Previously, we showed immune-related adverse events (IRAE) and objective, durable clinical responses in patients with metastatic melanoma treated with CTLA-4 blockade.We have now tr...

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書誌詳細
主要な著者: Downey, Stephanie G., Klapper, Jacob A., Smith, Franz O., C.Yang, James, Sherry, Richard M., Royal, Richard E., Kammula, Udai S., Hughes, Marybeth S., Allen, Tamika E., Levy, Catherine L., Michael, Yellin, Nichol, Geoffrey, E.White, Donald, Steinberg, Seth M., Rosenberg, Steven A.
フォーマット: Artigo
言語:Inglês
出版事項: 2007
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2147083/
https://ncbi.nlm.nih.gov/pubmed/17982122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-0187
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