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Bub1 Is a Fission Yeast Kinetochore Scaffold Protein, and Is Sufficient to Recruit other Spindle Checkpoint Proteins to Ectopic Sites on Chromosomes

The spindle checkpoint delays anaphase onset until all chromosomes have attached in a bi-polar manner to the mitotic spindle. Mad and Bub proteins are recruited to unattached kinetochores, and generate diffusible anaphase inhibitors. Checkpoint models propose that Mad1 and Bub1 act as stable kinetoc...

詳細記述

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書誌詳細
主要な著者: Rischitor, Patricia E., May, Karen M., Hardwick, Kevin G.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2147072/
https://ncbi.nlm.nih.gov/pubmed/18094750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001342
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