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Recombinant modified vaccinia virus Ankara–simian immunodeficiency virus gag pol elicits cytotoxic T lymphocytes in rhesus monkeys detected by a major histocompatibility complex class I/peptide tetramer

The utility of modified vaccinia virus Ankara (MVA) as a vector for eliciting AIDS virus-specific cytotoxic T lymphocytes (CTL) was explored in the simian immunodeficiency virus (SIV)/rhesus monkey model. After two intramuscular immunizations with recombinant MVA-SIV(SM) gag pol, the monkeys develop...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Seth, Aruna, Ourmanov, Ilnour, Kuroda, Marcelo J., Schmitz, Jörn E., Carroll, Miles W., Wyatt, Linda S., Moss, Bernard, Forman, Meryl A., Hirsch, Vanessa M., Letvin, Norman L.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1998
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21470/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9707609/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.17.10112
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