Targeted gene disruption reveals a role for natural secretory IgM in the maturation of the primary immune response

Accelerated development of the secondary immune response may be attributable in part to the rapid delivery of antigen to lymphoid follicles by circulating antibody elicited on primary immunization. Here we provide evidence indicating that the nonspecific IgM present in naive mice (natural antibody)...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ehrenstein, Michael R., O’Keefe, Theresa L., Davies, Sarah L., Neuberger, Michael S.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21466/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9707605/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.17.10089
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